CYP7B1 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of CYP7B1 expression in transfected 293T cell line (H00009420-T02) by CYP7B1 MaxPab polyclonal antibody.
Lane 1: CYP7B1 transfected lysate(58.30 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human CYP7B1 protein.
Immunogen
CYP7B1 (NP_004811.1, 1 a.a. ~ 506 a.a) full-length human protein.
Sequence
MAGEVSAATGRFSLERLGLPGLALAAALLLLALCLLVRRTRRPGEPPLIKGWLPYLGVVLNLRKDPLRFMKTLQKQHGDTFTVLLGGKYITFILDPFQYQLVIKNHKQLSFRVFSNKLLEKAFSISQLQKNHDMNDELHLCYQFLQGKSLDILLESMMQNLKQVFEPQLLKTTSWDTAELYPFCSSIIFEITFTTIYGKVIVCDNNKFISELRDDFLKFDDKFAYLVSNIPIELLGNVKSIREKIIKCFSSEKLAKMQGWSEVFQSRQDVLEKYYVHEDLEIGAHHLGFLWASVANTIPTMFWAMYYLLRHPEAMAAVRDEIDRLLQSTGQKKGSGFPIHLTREQLDSLICLESSIFEALRLSSYSTTIRFVEEDLTLSSETGDYCVRKGDLVAIFPPVLHGDPEIFEAPEEFRYDRFIEDGKKKTTFFKRGKKLKCYLMPFGTGTSKCPGRFFALMEIKQLLVILLTYFDLEIIDDKPIGLNYSRLLFGIQYPDSDVLFRYKVKS
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (67); Rat (66)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of CYP7B1 expression in transfected 293T cell line (H00009420-T02) by CYP7B1 MaxPab polyclonal antibody.
Lane 1: CYP7B1 transfected lysate(58.30 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — CYP7B1
Entrez GeneID
9420GeneBank Accession#
NM_004820.2Protein Accession#
NP_004811.1Gene Name
CYP7B1
Gene Alias
CBAS3, CP7B, SPG5A
Gene Description
cytochrome P450, family 7, subfamily B, polypeptide 1
Omim ID
603711Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, which converts cholesterol to bile acids. This enzyme likely plays a minor role in total bile acid synthesis, but may also be involved in the development of atherosclerosis, neurosteroid metabolism and sex hormone synthesis. [provided by RefSeq
Other Designations
cytochrome P450, subfamily VIIB (oxysterol 7 alpha-hydroxylase), polypeptide 1|oxysterol 7alpha-hydroxylase
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Interactome
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Pathway
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Disease
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