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FUS Split FISH Probe

  • Catalog # : FS0020
  • Visit Frequency :
  • Countries :
  • Specification
  • Product Description:
  • Labeled FISH probes for identification of gene split using Fluoresecent In Situ Hybridization Technique. (Technology)
  • Quality Control Testing:
  • Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.

    QC Testing of FS0020
  • Supplied Product:
  • DAPI Counterstain (1500 ng/mL ) 250 uL
  • Storage Instruction:
  • Store at 4°C in the dark.
  • Note:
  • Hybridization position of the probes on the chromosome:

  • Probe 1:
        Size:
        Fluorophore:
        Location:
  • FUS(Texas Red)
    Approximately 620kb
    Texas Red
    16p11.2
  • Probe 2:
        Size:
        Fluorophore:
        Location:
  • FUS(FITC)
    Approximately 410kb
    FITC
    16p11.2
  • Origin:
  • Human
  • Source:
  • Genomic DNA
  • Notice:
  • We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
  • Regulation Status:
  • For research use only (RUO)
  • Applications
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections) enlargeenlarge this image
  • Human pancreatic cancer (FFPE) stained with FUS Split FISH Probe. Human pancreatic cancer showed no FUS gene split.
  • Protocol Download
  • Application Image
  • Fluorescent In Situ Hybridization (Cell)
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 2521
  • Gene Name:
  • FUS
  • Gene Alias:
  • CHOP,FUS-CHOP,FUS1,TLS,TLS/CHOP,hnRNP-P2
  • Gene Description:
  • fusion (involved in t(12;16) in malignant liposarcoma)
  • Gene Summary:
  • This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6. [provided by RefSeq
  • Other Designations:
  • FUS-CHOP fusion protein,FUS-CHOP protein fusion,Fusion gene in myxoid liposarcoma,fus-like protein,fus/tls-chop oncogene,heterogeneous nuclear ribonucleoprotein P2,translocated in liposarcoma
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