NOTCH 2 recombinant monoclonal antibody, clone B9
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Immunofluorescence
Immunofluorescence analysis of NOTCH2 (green) in HeLa cell lysates using anti-Notch 2 recombinant monoclonal antibody, clone B9 (Cat # RAB02800), and DAPI(blue).
-
Specification
Product Description
Rabbit recombinant monoclonal antibody raised against NRR of mouse Notch 2.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to NRR of mouse Notch 2
Reactivity
Mouse
Form
Liquid
Conjugation
Unconjugated
Concentration
batch dependent
Isotype
IgG kappa
Recommend Usage
Blocking
ELISA
Immunofluorescence
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS with 0.02% Proclin 300
Storage Instruction
Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Immunofluorescence
Immunofluorescence analysis of NOTCH2 (green) in HeLa cell lysates using anti-Notch 2 recombinant monoclonal antibody, clone B9 (Cat # RAB02800), and DAPI(blue).Enzyme-linked Immunoabsorbent Assay
Blocking
-
Gene Info — NOTCH2
Entrez GeneID
4853Protein Accession#
Q04721(human)<br>O35516(mouse)Gene Name
NOTCH2
Gene Alias
AGS2, hN2
Gene Description
Notch homolog 2 (Drosophila)
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play a role in vascular, renal and hepatic development. [provided by RefSeq
Other Designations
OTTHUMP00000014035|OTTHUMP00000059536|notch 2
-
Interactome
-
Pathway
-
Disease
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com