CXCR1 recombinant monoclonal antibody, clone SE2
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Specification
Product Description
Mouse recombinant monoclonal antibody raised against human CXCR1.
Antibody Species
Mouse
Immunogen
Original antibody is raised against a BSA-conjugated peptide comprising of the N-terminal part of IL-8RA (amino acids 1-30).
Reactivity
Human
Form
Liquid
Isotype
IgG2b kappa
Recommend Usage
Flow Cytometry
Immunohistochemistry
Western Blot
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% Proclin 300)
Storage Instruction
Store at 4°C for 3 months. For long term storage, aliquot and store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Immunohistochemistry
Flow Cytometry
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Gene Info — CXCR1
Entrez GeneID
3577Gene Name
CXCR1
Gene Alias
C-C, C-C-CKR-1, CD128, CD181, CDw128a, CKR-1, CMKAR1, IL8R1, IL8RA, IL8RBA
Gene Description
chemokine (C-X-C motif) receptor 1
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. [provided by RefSeq
Other Designations
receptor|alpha|interleukin-8 receptor type 1|interleukin-8 receptor type A
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Interactome
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Pathway
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Disease
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