TNFRSF8 recombinant monoclonal antibody, clone Ki-3
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Specification
Product Description
Mouse recombinant monoclonal antibody raised against human TNFRSF8.
Antibody Species
Mouse
Immunogen
Original antibody is raised against recombinant protein corresponding to human TNFRSF8.
Reactivity
Human
Form
Liquid
Isotype
IgG2b kappa
Recommend Usage
ELISA
Flow Cytometry
Immunofluorescence
Immunohistochemistry
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS with 0.02% Proclin 300
Storage Instruction
Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Immunohistochemistry
Immunofluorescence
Enzyme-linked Immunoabsorbent Assay
Flow Cytometry
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Gene Info — TNFRSF8
Entrez GeneID
943Gene Name
TNFRSF8
Gene Alias
CD30, D1S166E, KI-1
Gene Description
tumor necrosis factor receptor superfamily, member 8
Omim ID
153243Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq
Other Designations
CD30 antigen|CD30L receptor|Ki-1 antigen|OTTHUMP00000001783|cytokine receptor CD30|lymphocyte activation antigen CD30
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