CHUK recombinant monoclonal antibody
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human CHUK.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide of human IKK alpha.
Theoretical MW (kDa)
85
Reactivity
Human
Specificity
Recognizes endogenous levels of IKK alpha protein.
Form
Liquid
Purification
Immunogen affinity chromatography
Isotype
IgG
Recommend Usage
Immunoprecipitation(1:10-1:50)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50mM Tris-Glycine, pH 7.4 (0.15M NaCl, 50% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at 4°C short term.
Aliquot and store at -20°C long term.
Avoid freeze-thaw cycles.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of Jurkat (A), Hela (B) whole cell lysates with IKK alpha recombinant monoclonal antibody (Cat # RAB02440).Immunoprecipitation
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Gene Info — CHUK
Entrez GeneID
1147Protein Accession#
O15111Gene Name
CHUK
Gene Alias
IKBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16
Gene Description
conserved helix-loop-helix ubiquitous kinase
Omim ID
600664Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. [provided by RefSeq
Other Designations
I-kappa-B kinase 1|I-kappa-B kinase-alpha|IKK-a kinase|IkB kinase alpha subunit|Nuclear factor NFkappaB inhibitor kinase alpha|OTTHUMP00000020273|conserved helix-loop ubiquitous kinase
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Interactome
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Pathway
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Disease
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