XPO1 recombinant monoclonal antibody, clone R01-9J7
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human XPO1.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human XPO1.
Theoretical MW (kDa)
Calculated MW: 123 k
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunofluorescence(1:50-1:200)
Immunohistochemistry (1:50-1:100)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM Tris-Glycine, pH 7.4 (0.15 M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at -20 °C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry
Immunofluorescence
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Gene Info — XPO1
Entrez GeneID
7514Protein Accession#
O14980Gene Name
XPO1
Gene Alias
CRM1, DKFZp686B1823
Gene Description
exportin 1 (CRM1 homolog, yeast)
Omim ID
602559Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1. [provided by RefSeq
Other Designations
CRM1, yeast, homolog|Exportin-1 (required for chromosome region maintenance)|exportin 1|exportin 1 (CRM1, yeast, homolog)
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Interactome
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