GSTP1 polyclonal antibody
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of GSTP1.
Immunogen
A synthetic peptide corresponding to amino acids at C-terminus of human GSTP1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
Identical to the related rat and mouse sequence.
Form
Lyophilized
Purification
Immunoaffinity purification
Isotype
IgG
Recommend Usage
Western Blot (1 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from 0.9 mg NaCl, 0.2 mg Na2HPO4 (5 mg BSA, 0.05 mg sodium azide, 0.05 mg Thimerosal)
Storage Instruction
Store at -20°C on dry atmosphere.
After reconstitution with 200 uL of deionized water and concentration will be 500 ug/mL, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide and thimerosal: POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of HeLa cell lysate. Using GSTP1 polyclonal antibody (Cat # PAB7980).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of paraffin-embedded human endometrial cancer with GSTP1 polyclonal antibody (Cat # PAB7980). Staining GST in cytoplasma DAB chromogenic reaction. -
Gene Info — GSTP1
Entrez GeneID
2950Gene Name
GSTP1
Gene Alias
DFN7, FAEES3, GST3, PI
Gene Description
glutathione S-transferase pi 1
Omim ID
134660Gene Ontology
HyperlinkGene Summary
Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases. [provided by RefSeq
Other Designations
OTTHUMP00000174659|deafness, X-linked 7|fatty acid ethyl ester synthase III|glutathione transferase
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Interactome
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Pathway
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Disease
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Publication Reference
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Placental glutathione-S-transferase-pi mRNA is abundantly expressed in human skin.
Konohana A, Konohana I, Schroeder WT, O'Brien WR, Amagai M, Greer J, Shimizu N, Gammon WR, Siciliano MJ, Duvic M.
The Journal of Investigative Dermatology 1990 Aug; 95(2):119.
Application:WB-Ce, WB-Ti, Human , Human epidermal keratinocytes, Human epidermis.
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Chromosomal localization of human glutathione transferase genes of classes alpha, mu and pi.
Islam MQ, Platz A, Szpirer J, Szpirer C, Levan G, Mannervik B.
Human Genetics 1989 Jul; 82(4):338.
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Structure of the human genomic glutathione S-transferase-pi gene.
Morrow CS, Cowan KH, Goldsmith ME.
Gene 1989 Jan; 75(1):3.
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Placental glutathione-S-transferase-pi mRNA is abundantly expressed in human skin.
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