NME1 polyclonal antibody

Catalog # PAB3290

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Size:400 uL
Price: USD $ 329.00
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  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
Images
Western Blot (Cell lysate)
Application

Western Blot (Cell lysate)

The NME1 polyclonal antibody (Cat # PAB3290) is used in Western blot to detect NME1 in A-375 cell lysate.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Application

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

Formalin-fixed and paraffin-embedded human cancer tissue reacted with NME1 polyclonal antibody (Cat # PAB3290) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma.

  • Specifications

    Product Description

    Rabbit polyclonal antibody raised against synthetic peptide of NME1.

    Immunogen

    A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human NME1.

    Host

    Rabbit

    Reactivity

    Human

    Form

    Liquid

    Purification

    Protein G purification

    Recommend Usage

    Immunofluorescence (1:10-50)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-100)
    Western Blot (1:1000)
    The optimal working dilution should be determined by the end user.

    Storage Buffer

    In PBS (0.09% sodium azide)

    Storage Instruction

    Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.

    Note

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

  • Applications

    Western Blot (Cell lysate)

    The NME1 polyclonal antibody (Cat # PAB3290) is used in Western blot to detect NME1 in A-375 cell lysate.

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

    Formalin-fixed and paraffin-embedded human cancer tissue reacted with NME1 polyclonal antibody (Cat # PAB3290) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma.

    Immunofluorescence

  • Gene Info — NME1

    Entrez GeneID

    4830

    Protein Accession#

    P15531

    Gene Name

    NME1

    Gene Alias

    AWD, GAAD, NB, NBS, NDPK-A, NDPKA, NM23, NM23-H1

    Gene Description

    non-metastatic cells 1, protein (NM23A) expressed in

    Omim ID

    156490 256700

    Gene Ontology

    Hyperlink

    Gene Summary

    This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq

    Other Designations

    NDP kinase A|OTTHUMP00000174772

  • Interactomes
  • Pathways
  • Diseases
  • Publication Reference
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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