COL3A1 polyclonal antibody

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Specifications
Product Description
Rabbit polyclonal antibody raised against partial recombinant human COL3A1.
Immunogen
Recombinant protein corresponding to human COL3A1.
Sequence
RGERGSEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAIAGIGGEKAGGFAPYYGDEPMDFKINTDEIMTSLKSVNGQIESLISPDGSRKNPARNCRDLKFCHPE
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-1:200)
Western Blot (1:100-1:250)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of HeLa cell lysate with COL3A1 polyclonal antibody (Cat # PAB31390).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human nasopharynx with COL3A1 polyclonal antibody (Cat # PAB31390) shows distinct positivity in fibroblasts. -
Gene Info — COL3A1
Entrez GeneID
1281Protein Accession#
P02461Gene Name
COL3A1
Gene Alias
EDS4A, FLJ34534
Gene Description
collagen, type III, alpha 1
Gene Ontology
HyperlinkGene Summary
This gene encodes the pro-alpha1 chains of type III collagen, a fibrillar collagen that is found in extensible connective tissues such as skin, lung, uterus, intestine and the vascular system, frequently in association with type I collagen. Mutations in this gene are associated with Ehlers-Danlos syndrome types IV, and with aortic and arterial aneurysms. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish
Other Designations
Ehlers-Danlos syndrome type IV, autosomal dominant|alpha1 (III) collagen|collagen type III alpha 1|collagen, fetal
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Interactomes
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Diseases
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