NOS2 (phospho Y151) polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic phosphopeptide of human NOS2.
Immunogen
Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y151 of human NOS2.
Host
Rabbit
Theoretical MW (kDa)
131
Reactivity
Human, Mouse
Specificity
This antibody detects endogenous levels of NOS2 only when phosphorylated at tyrosine 151.
Form
Liquid
Purification
Affinity purification
Recommend Usage
Immunohistochemistry (1:50-1:100)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (without Mg2+ and Ca2+), (50% glycerol, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Avoid repeated freezing and thawing. -
Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human colon carcinoma tissue by NOS2 (phospho Y151) polyclonal antibody (Cat # PAB29225) without blocking peptide (A) or preincubated with blocking peptide (B) under 1:50-1:100 dilution. -
Gene Info — NOS2
Entrez GeneID
4843Protein Accession#
P35228Gene Name
NOS2
Gene Alias
HEP-NOS, INOS, NOS, NOS2A
Gene Description
nitric oxide synthase 2, inducible
Gene Ontology
HyperlinkGene Summary
Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. This gene encodes a nitric oxide synthase which is expressed in liver and is inducible by a combination of lipopolysaccharide and certain cytokines. Three related pseudogenes are located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq
Other Designations
NOS, type II|nitric oxide synthase 2A|nitric oxide synthase 2A (inducible, hepatocytes)|nitric oxide synthase, macrophage
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Interactome
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Pathway
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Disease
- Acute Disease
- Adenocarcinoma
- Albuminuria
- Alzheimer disease
- Anemia
- Angina
- Angina Pectoris
- Arthritis
- Asthma
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