DCX polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
DCX polyclonal antibody (Cat # PAB29068) was validated by immunocytological staining (at a concentration of 2 ug/mL).
DCX-staining of cochlear neurons in the cochlear ganglion of an adult mouse brain (green staining). Red staining is neurofilament immunoreactivity with a rabbit antibody.
-
Specification
Product Description
Chicken polyclonal antibody raised against recombinant Human DCX.
Immunogen
Two different KLH-conjugated synthetic peptides corresponding to different regions of DCX gene product, shared between the human (CAA06617.1, NCBI) and mouse (AAT58219.1, NCBI) sequences.
Host
Chicken
Reactivity
Human, Mouse
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgY
Quality Control Testing
Immunocytochemistry
DCX polyclonal antibody (Cat # PAB29068) was validated by immunocytological staining (at a concentration of 2 ug/mL).
DCX-staining of cochlear neurons in the cochlear ganglion of an adult mouse brain (green staining). Red staining is neurofilament immunoreactivity with a rabbit antibody.Recommend Usage
Immunocytochemistry(1:1000-1:2000)
Immunohistochemistry(1:1000-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.02% sodium azide)
Storage Instruction
Store at 4°C and avoid from light.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Immunohistochemistry
Immunocytochemistry
-
Gene Info — DCX
Entrez GeneID
1641Protein Accession#
CAA06617.1Gene Name
DCX
Gene Alias
DBCN, DC, LISX, SCLH, XLIS
Gene Description
doublecortin
Gene Ontology
HyperlinkGene Summary
In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The protein encoded by this gene is a cytoplasmic protein which appears to direct neuronal migration by regulating the organization and stability of microtubules. The encoded protein contains two doublecortin domains, which bind microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in this gene are a cause of X-linked lissencephaly. Multiple transcript variants encoding at least three different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000062892|doublecortex|doublin|lissencephalin-X
-
Gene Info — Dcx
Entrez GeneID
13193Protein Accession#
CAA06617.1Gene Name
Dcx
Gene Alias
Dbct
Gene Description
doublecortin
Gene Ontology
HyperlinkGene Summary
X-linked (doublecortin)
Other Designations
OTTMUSP00000020397|doublecortex|lissencephaly, X-linked (doublecortin)
-
Interactome
-
Disease
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com