HDAC4 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of extracts from Jurkat cells using HDAC4 polyclonal antibody (Cat # PAB26709).
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Specifications
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of HDAC4.
Immunogen
A synthetic peptide corresponding to residues surrounding S632 of human HDAC4.
Sequence
A-Q-Sp-S-P
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Affinity chromatography
Concentration
1 mg/mL
Recommend Usage
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (without Mg2+ and Ca2+), 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of extracts from Jurkat cells using HDAC4 polyclonal antibody (Cat # PAB26709). -
Gene Info — HDAC4
Entrez GeneID
9759Protein Accession#
P56524Gene Name
HDAC4
Gene Alias
HA6116, HD4, HDAC-A, HDACA, KIAA0288
Gene Description
histone deacetylase 4
Omim ID
605314Gene Ontology
HyperlinkGene Summary
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq
Other Designations
histone deacetylase A
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Interactomes
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Diseases
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