ANGPT2 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of ANGPT2.
Immunogen
A synthetic peptide corresponding to 18 amino acids at C-terminus of human ANGPT2.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
At least three isoforms of ANGPT2 are known to exist; this antibody will detect all three isoforms.
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Isotype
IgG
Recommend Usage
Western Blot (1-2 ug/mL)
Immunohistochemistry (2.5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of ANGPT2 in human liver tissue with ANGPT2 polyclonal antibody (Cat # PAB25796) at (lane 1) 1 and (lane 2) 2 ug/mL.Immunohistochemistry
Immunohistochemical analysis of ANGPT2 in mouse liver tissue with ANGPT2 polyclonal antibody (Cat # PAB25796) at 2.5 ug/mL.Enzyme-linked Immunoabsorbent Assay
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Gene Info — ANGPT2
Entrez GeneID
285Protein Accession#
P_001138Gene Name
ANGPT2
Gene Alias
AGPT2, ANG2
Gene Description
angiopoietin 2
Omim ID
601922Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE-2, TEK). The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq
Other Designations
Tie2-ligand|angiopoietin-2|angiopoietin-2B|angiopoietin-2a
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Interactome
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