CEBPE polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of CEBPE.
Immunogen
A synthetic peptide corresponding to residues surrounding T74 of human CEBPE.
Host
Rabbit
Reactivity
Human
Specificity
This antibody is specific to CEBPE.
Form
Liquid
Purification
Affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:100)
Immunofluorescence (1:500-1:1000)
ELISA (1:5000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Cell lysate)
Western blot analysis of extracts from HUVEC cells, treated with Insulin (0.01 U /ml, 15 mins), using CEBPE polyclonal antibody (Cat # PAB18310).
Peptide "+" means "peptide blocking".Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human brain tissue using CEBPE polyclonal antibody (Cat # PAB18310).
Peptide "+" means "peptide blocking".Immunofluorescence
Immunofluorescence analysis of HeLa cells, using CEBPE polyclonal antibody (Cat # PAB18310).
Peptide "+" means "peptide blocking".Enzyme-linked Immunoabsorbent Assay
-
Gene Info — CEBPE
Entrez GeneID
1053Protein Accession#
Q15744Gene Name
CEBPE
Gene Alias
C/EBP-epsilon, CRP1
Gene Description
CCAAT/enhancer binding protein (C/EBP), epsilon
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-delta. The encoded protein may be essential for terminal differentiation and functional maturation of committed granulocyte progenitor cells. Mutations in this gene have been associated with Specific Granule Deficiency, a rare congenital disorder. Multiple variants of this gene have been described, but the full-length nature of only one has been determined. [provided by RefSeq
Other Designations
CCAAT/enhancer binding protein epsilon
-
Interactome
-
Disease
-
Publication Reference
-
Increased CCAAT enhancer-binding protein epsilon (C/EBPepsilon) expression and premature apoptosis in myeloid cells expressing Gfi-1 N382S mutant associated with severe congenital neutropenia.
Zhuang D, Qiu Y, Kogan SC, Dong F.
The Journal of Biological Chemistry 2006 Apr; 281(16):10745.
Application:WB-Tr, Mouse, 32D, 32D-Gfi-1, 32D-N382S, 32D-CEBPE, L-G, L-G-N382S cells.
-
C/EBP epsilon mediates myeloid differentiation and is regulated by the CCAAT displacement protein (CDP/cut).
Khanna-Gupta A, Zibello T, Sun H, Lekstrom-Himes J, Berliner N.
Proceedings of the National Academy of Sciences of the United States of America 2001 Jul; 98(14):8000.
-
The role of C/EBP(epsilon) in the terminal stages of granulocyte differentiation.
Lekstrom-Himes JA.
Stem Cells 2001 Jan; 19(2):125.
-
Increased CCAAT enhancer-binding protein epsilon (C/EBPepsilon) expression and premature apoptosis in myeloid cells expressing Gfi-1 N382S mutant associated with severe congenital neutropenia.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com