SLC7A11 polyclonal antibody (Biotin)
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of SLC7A11.
Immunogen
A synthetic peptide corresponding to amino acids 1-50 of human SLC7A11.
Host
Rabbit
Reactivity
Human, Mouse
Specificity
This antibody reacts with the human and mouse proteins. Other species have not been tested. This is specific to XCT. By Western blot a band at ~55 KDa is seen. Immunoprecipitation is not recommended.
Form
Liquid
Conjugation
Biotin
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS
Storage Instruction
Store at 4°C. Do not freeze.
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Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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Gene Info — SLC7A11
Entrez GeneID
23657Gene Name
SLC7A11
Gene Alias
CCBR1, xCT
Gene Description
solute carrier family 7, (cationic amino acid transporter, y+ system) member 11
Omim ID
607933Gene Ontology
HyperlinkGene Summary
SLC7A11 is a member of a heteromeric Na(+)-independent anionic amino acid transport system highly specific for cystine and glutamate. In this system, designated system Xc(-), the anionic form of cystine is transported in exchange for glutamate.[supplied by OMIM
Other Designations
cystine/glutamate transporter
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Interactome
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Disease
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