MYD88 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of MYD88.
Immunogen
A synthetic peptide corresponding to amino acids 233-248 of human MYD88.
Host
Rabbit
Reactivity
Human
Specificity
Differ from those of mouse by two amino acids. an approximately 35 KDa band can be detected. It is human and mouse reactive.
Form
Liquid
Recommend Usage
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of MYD88 in Jurkat whole cell lysate with MYD88 polyclonal antibody (Cat # PAB13080) at 1 : 500 dilution.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human heart tissue using MYD88 polyclonal antibody (Cat # PAB13080) at 2 ug/mL . -
Gene Info — MYD88
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Interactome
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Pathway
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Disease
- Arthritis
- Asthma
- Birth Weight
- Cardiovascular Diseases
- Chronic Disease
- Coronary Disease
- Cystitis
- Diabetes Mellitus
- Edema
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Publication Reference
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Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function.
Adachi O, Kawai T, Takeda K, Matsumoto M, Tsutsui H, Sakagami M, Nakanishi K, Akira S.
Immunity 1998 Jul; 9(1):143.
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IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling.
Muzio M, Ni J, Feng P, Dixit VM.
Science 1997 Nov; 278(5343):1612.
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Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function.
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