ASAP3 polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot (Transfected lysate)
Western blot using ASAP3 polyclonal antibody (Cat # PAB11289) shows detection of ASAP3 in NIH/3T3 cells over-expressing the protein.
Cell extracts (5 ug) were resolved by SDS PAGE.
The membrane was probed with ASAP3 polyclonal antibody at a 1 : 10,000 dilution.
Personal Communication, Vi Luan HA, CCR-NCI, Bethesda, MD.
-
Specification
Product Description
Rabbit polyclonal antibody raised against recombinant ASAP3.
Immunogen
Recombinant protein corresponding to human ASAP3.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Recommend Usage
ELISA (1:1000-1:5000)
Western Blot (1:1000-1:10000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 20 mM KH2PO4, 150 mM NaCl, pH 7.2 (0.01% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Transfected lysate)
Western blot using ASAP3 polyclonal antibody (Cat # PAB11289) shows detection of ASAP3 in NIH/3T3 cells over-expressing the protein.
Cell extracts (5 ug) were resolved by SDS PAGE.
The membrane was probed with ASAP3 polyclonal antibody at a 1 : 10,000 dilution.
Personal Communication, Vi Luan HA, CCR-NCI, Bethesda, MD.Immunohistochemistry
Enzyme-linked Immunoabsorbent Assay
-
Gene Info — ASAP3
Entrez GeneID
55616Protein Accession#
BAB85677;Q8TDY4Gene Name
ASAP3
Gene Alias
ACAP4, CENTB6, DDEFL1, FLJ20199, UPLC1
Gene Description
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of a subfamily of ADP-ribosylation factor(Arf) GTPase-activating proteins that contain additional ankyrin repeat and pleckstrin homology domains. The Arf GAP domain of this protein catalyzes the hydrolysis of GTP bound to Arf proteins. The encoded protein promotes cell differentiation and migration and has been implicated in cancer cell invasion. Alternative splicing results in multiple transcript variants. [provided by RefSeq
Other Designations
ARF6 GTPase-activating protein|ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 1|OTTHUMP00000003268|centaurin, beta 6|development and differentiation enhancing factor-like 1|up-regulated in liver cancer 1 (UPLC1)
-
Interactome
-
Pathway
-
Publication Reference
-
Arf GAPs and their interacting proteins.
Inoue H, Randazzo PA.
Traffic 2007 Nov; 8(11):1465.
-
Expression of AMAP1, an ArfGAP, provides novel targets to inhibit breast cancer invasive activities.
Onodera Y, Hashimoto S, Hashimoto A, Morishige M, Mazaki Y, Yamada A, Ogawa E, Adachi M, Sakurai T, Manabe T, Wada H, Matsuura N, Sabe H.
The EMBO Journal 2005 Mar; 24(5):963.
-
Isolation of development and differentiation enhancing factor-like 1 (DDEFL1) as a drug target for hepatocellular carcinomas.
Okabe H, Furukawa Y, Kato T, Hasegawa S, Yamaoka Y, Nakamura Y.
International Journal of Oncology 2004 Jan; 24(1):43.
-
Arf GAPs and their interacting proteins.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com