OSMR (Human) Recombinant Protein
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
Human OSMR (Q99650-1, Glu28-Met740) partial recombinant protein with His tag at C-Terminus expressed in HEK293 cells.
Sequence
Glu28-Met740
Host
Human
Theoretical MW (kDa)
82.2
Form
Lyophilized
Preparation Method
Mammalian cell (HEK293) expression system
Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin Level
< 1 EU per 1 ug of protein (determined by LAL method)
Activity
The EC50 was 4.4 ng/mL, messured by ELISA at 1 ug/mL.
Quality Control Testing
SEC-HPLC and Tris-Bis PAGE
SEC-HPLC
The purity of Human OSMR is greater than 95% as determined by SEC-HPLC.
Tris-Bis PAGE
Human OSMR on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. You may also be interested in Human CRTAM Protein (CRM-HM101) From $338.00 Human FcRn Protein (FRN-HM101) From $404.00 Human LGMN Protein (LGM-HM101) From $300.00 Human AGER Protein (AER-HM101) From $338.00 View more associated products Recently Viewed Products
Recommend Usage
Biological Activity
ELISA
SDS-PAGE
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from sterile distilled Water is > 100 ug/mL
Storage Instruction
Store at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing.Note
Result of bioactivity analysis
-
Applications
Enzyme-linked Immunoabsorbent Assay
Immobilized Human OSMR, His Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Anti-OSMR Antibody, hFc Tag with the EC50 of 4.4ng/ml determined by ELISA.Functional Study
SDS-PAGE
-
Gene Info — OSMR
Entrez GeneID
9180Protein Accession#
Q99650-1Gene Name
OSMR
Gene Alias
MGC150626, MGC150627, MGC75127, OSMRB
Gene Description
oncostatin M receptor
Omim ID
601743Gene Ontology
HyperlinkGene Summary
Oncostatin M is a member of the IL6 family of cytokines. Functional receptors for IL6 family cytokines are multisubunit complexes involving members of the hematopoietin receptor superfamily. Many IL6 cytokines utilize gp130 as a common receptor subunit. OSM binds to the gp130 receptor subunit and, in association with the leukemia inhibitory factor receptor, induces a proliferative response in permissive cells. OSMR is an alternative subunit (for an OSM receptor complex (a heterodimer of gp130 and OSMR) that is activated by OSM but not by LIF [provided by RefSeq
Other Designations
-
-
Interactome
-
Pathway
-
Disease
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com