CD207 (Human) Recombinant Protein
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Specification
Product Description
Human CD207 partial recombinant protein with His tag in C-terminus expressed in Escherichia coli.
Sequence
ADPPRFMGTISDVKTNVQLLKGRVDNISTLDSEIKKNSDGMEAAGVQIQMVNESLGYVRSQFLKLKTSVEKANAQIQILTRSWEEVSTLNAQIPELKSDLEKASALNTKIRALQGSLENMSKLLKRQNDILQVVSQGWKYFKGNFYYFSLIPKTWYSAEQFCVSRNSHLTSVTSESEQEFLYKTAGGLIYWIGLTKAGMEGDWSWVDDTPFNKVQSARFWIPGEPNNAGNNEHCGNIKAPSLQAWNDAPCDKTFLFICKRPYVPSEPHHHHHH
Host
Viruses
Theoretical MW (kDa)
30.9
Form
Liquid
Preparation Method
Escherichia coli expression system
Purification
chromatographic
Purity
> 90% as determined by SDS-PAGE.
Storage Buffer
Solution (1 mg/mL) containing 1X PBS, pH 7.4, 10% glycerol.
Storage Instruction
Store at 4°C for one weeks and should be stored at -20°C to -80°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid repeated freeze/thaw cycles. -
Applications
SDS-PAGE
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Gene Info — CD207
Entrez GeneID
50489Protein Accession#
Q9UJ71Gene Name
CD207
Gene Alias
CLEC4K
Gene Description
CD207 molecule, langerin
Omim ID
604862Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. [provided by RefSeq
Other Designations
C-type lectin domain family 4, member K|CD207 antigen, langerin|Langerhans cell specific c-type lectin
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