CSFR3 (Human) Recombinant Protein

Catalog # P6762

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Price

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Quantity

Size:100 ug
Price: USD $ 479.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
Images
QC Test

CSFR3 (Human) Recombinant Protein (Cat #P6762) was determined by SDS-PAGE with Coomassie Blue, showing a band at 90-105 kDa.

Result of activity analysis
Note

Result of activity analysis

Result of activity analysis

  • Specification

    Product Description

    Human CSFR3 (NP_000751.1, 25 a.a. - 621 a.a.) partial recombinant protein with His tag at C-terminus expressed in HEK293 cells.Bioactive Protein,Bioactive Proteins,Bioactive,Active,Functional Protein,Functional Proteins,Recombinant Human Protein,Recombinant Human Proteins,Human Recombinant Protein,Human Recombinant Proteins,HuPro

    Host

    Human

    Theoretical MW (kDa)

    90-105

    Form

    Lyophilized

    Preparation Method

    Mammalian cell (HEK293) expression system

    Purification

    Ni-sepharose purification

    Purity

    > 95% by SDS-PAGE

    Endotoxin Level

    < 0.1 EU/ug

    Activity

    Measured by the ability to inhibit the GCSF-induced proliferation of M-NFS-60 mouse myelogenous leukemia lymphoblast cells.The ED50 for this effect is typically 31.5-126 ng/mL.

    Quality Control Testing

    SDS-PAGE Stained with Coomassie Blue

    CSFR3 (Human) Recombinant Protein (Cat #P6762) was determined by SDS-PAGE with Coomassie Blue, showing a band at 90-105 kDa.

    Recommend Usage

    SDS-PAGE
    The optimal working dilution should be determined by the end user.

    Storage Buffer

    Lyophilized from PBS, pH 7.4.

    Storage Instruction

    Store the lyophilized protein at -20°C to -80°C for long term.
    After reconstitution to a concentration of 0.1-0.5 mg/mL in sterile distilled water, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
    Aliquot to avoid repeated freezing and thawing.

    Note

    Result of activity analysis

  • Applications

    SDS-PAGE

  • Gene Info — CSF3R

    Entrez GeneID

    1441

    Protein Accession#

    Q99062

    Gene Name

    CSF3R

    Gene Alias

    CD114, GCSFR

    Gene Description

    colony stimulating factor 3 receptor (granulocyte)

    Omim ID

    138971

    Gene Ontology

    Hyperlink

    Gene Summary

    The protein encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Four transcript variants encoding four different isoforms have been found for this gene, with three of the isoforms being membrane-bound and the other being secreted and soluble. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia. [provided by RefSeq

    Other Designations

    CD114 antigen|OTTHUMP00000009703|OTTHUMP00000009704|OTTHUMP00000009705|colony stimulating factor 3 receptor|granulocyte colony stimulating factor receptor

  • Interactome
  • Pathway
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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