AICDA monoclonal antibody, clone P2D3AT
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Specification
Product Description
Mouse monoclonal antibody raised against synthetic peptide of human AICDA, clone P2D3AT.
Immunogen
A synthetic peptide corresponding to amino acids 1-54 of human AICDA purified from Escherichia Coli.
Host
Mouse
Form
Liquid
Purification
Protein-G affinity chromatography
Isotype
Mouse IgG1 heavy chain and kappa light chain
Recommend Usage
Western Blot
ELISA
The Western blot analysis is 1:500 ~ 1,000. Recommended starting dilution is 1:500.Storage Buffer
In PBS, pH 7.4 and 0.1% Sodium Azide
Storage Instruction
Store at 4°C for 1 month.
After reconstitution with 1 mL of deionized water, store at -20°C for 12 months.
Aliquot to avoid repeated freezing and thawing. -
Applications
SDS-PAGE
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Gene Info — AICDA
Entrez GeneID
57379Gene Name
AICDA
Gene Alias
AID, ARP2, CDA2, HIGM2
Gene Description
activation-induced cytidine deaminase
Gene Ontology
HyperlinkGene Summary
This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2). [provided by RefSeq
Other Designations
activation-induced deaminase|integrated into Burkitt's lymphoma cell line Ramos
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Interactome
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Pathway
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Disease
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