VPS26A monoclonal antibody, clone AEEE-22
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic protein of human VPS26A.
Immunogen
A synthetic peptide corresponding to human VPS26A.
Host
Rabbit
Reactivity
Human
Specificity
This antibody reacts with human, mouse, rat VPS26A, in native form and recombinant. Superfamily members of VPS26A are not reactive to antibody.
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Western Blot (1:500-2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot (cell lysate) analysis of A-431 cell lysate. -
Gene Info — VPS26A
Entrez GeneID
9559Protein Accession#
O75436Gene Name
VPS26A
Gene Alias
FLJ12930, HB58, Hbeta58, PEP8A, VPS26
Gene Description
vacuolar protein sorting 26 homolog A (S. pombe)
Omim ID
605506Gene Ontology
HyperlinkGene Summary
This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
OTTHUMP00000019721|vacuolar protein sorting 26 A
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Interactome
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