IL9R monoclonal antibody, clone 1C2A6
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant human IL9R.
Immunogen
Recombinant protein corresponding to amino acid 41-270 of human IL9R from E. coli.
Host
Mouse
Theoretical MW (kDa)
57.1
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Western Blot (1:500-1:2000)
Immunocytochemistry
Flow Cytometry (1:200-1:400)
Immunohistochemistry (1:200-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western blot analysis of (1) HEK293 cells, (2) IL9R-hIgGFc transfected HEK293 cell lysate.Enzyme-linked Immunoabsorbent Assay
ELISA analysis of IL9R monoclonal antibody, clone 1C2A6.Flow Cytometry
Flow cytometric analysis of Ramos cells with IL9R monoclonal antibody (green) and negative control (red). -
Gene Info — IL9R
Entrez GeneID
3581Gene Name
IL9R
Gene Alias
CD129
Gene Description
interleukin 9 receptor
Omim ID
300007Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9). The functional IL9 receptor complex requires this protein as well as the interleukin 2 receptor, gamma (IL2RG), a common gamma subunit shared by the receptors of many different cytokines. The ligand binding of this receptor leads to the activation of various JAK kinases and STAT proteins, which connect to different biologic responses. This gene is located at the pseudoautosomal regions of X and Y chromosomes. Genetic studies suggested an association of this gene with the development of asthma. Multiple pseudogenes on chromosome 9, 10, 16, and 18 have been described. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000024332
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