CYP1A1 monoclonal antibody, clone 6G5
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More Files
- More Functions
Western Blot (Recombinant protein)
Western Blot analysis of human CYP1A1 recombinant protein with CYP1A1 monoclonal antibody, clone 6G5 (Cat # MAB16333).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human liver with CYP1A1 monoclonal antibody, clone 6G5 (Cat # MAB16333).
Enzyme-linked Immunoabsorbent Assay
ELISA analysis with CYP1A1 monoclonal antibody, clone 6G5 (Cat # MAB16333).
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant human CYP1A1.
Immunogen
Recombinant protein corresponding to human CYP1A1 from E. coli.
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Purified
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% protein stabilizer, 0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Recombinant protein)
Western Blot analysis of human CYP1A1 recombinant protein with CYP1A1 monoclonal antibody, clone 6G5 (Cat # MAB16333).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human liver with CYP1A1 monoclonal antibody, clone 6G5 (Cat # MAB16333).Enzyme-linked Immunoabsorbent Assay
ELISA analysis with CYP1A1 monoclonal antibody, clone 6G5 (Cat # MAB16333). -
Gene Info — CYP1A1
Entrez GeneID
1543Protein Accession#
P04798Gene Name
CYP1A1
Gene Alias
AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX
Gene Description
cytochrome P450, family 1, subfamily A, polypeptide 1
Omim ID
108330Gene Ontology
HyperlinkGene Summary
This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. [provided by RefSeq
Other Designations
aryl hydrocarbon hydroxylase|cytochrome P1-450, dioxin-inducible|cytochrome P450 1A1|cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 1|flavoprotein-linked monooxygenase|xenobiotic monooxygenase
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Interactome
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Pathway
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Disease
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