CD37 monoclonal antibody, clone 2B8
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant CD37.
Immunogen
Recombinant protein corresponding to human CD37.
Host
Mouse
Theoretical MW (kDa)
31.7
Reactivity
Human, Mouse
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Immunofluorescence (1:200-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In ascites (0.03% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunofluorescence
Confocal immunofluorescence analysis of methanol-fixed BCBL-1 (upper) and L1210 (bottom) cells using CD37 monoclonal antibody, clone 2B8 (Cat # MAB10534)(green), showing membrane localization. Blue: DRAQ5 fluorescent DNA dye.Enzyme-linked Immunoabsorbent Assay
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Gene Info — CD37
Entrez GeneID
951Gene Name
CD37
Gene Alias
GP52-40, MGC120234, TSPAN26
Gene Description
CD37 molecule
Omim ID
151523Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It may play a role in T-cell-B-cell interactions. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
CD37 antigen|cell differentiation antigen 37|leukocyte surface antigen CD37|tetraspanin-26
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Interactome
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Pathway
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Disease
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