PLA2G12A rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human PLA2G12A peptide using ARM Technology.
Immunogen
A synthetic peptide of human PLA2G12A is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human PLA2G12A peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — PLA2G12A
Entrez GeneID
81579GeneBank Accession#
PLA2G12AGene Name
PLA2G12A
Gene Alias
GXII, PLA2G12, ROSSY
Gene Description
phospholipase A2, group XIIA
Omim ID
611652Gene Ontology
HyperlinkGene Summary
Secreted phospholipase A2 (sPLA2) enzymes liberate arachidonic acid from phospholipids for production of eicosanoids and exert a variety of physiologic and pathologic effects. Group XII sPLA2s, such as PLA2G12A, have relatively low specific activity and are structurally and functionally distinct from other sPLA2s (Gelb et al., 2000 [PubMed 11031251]).[supplied by OMIM
Other Designations
group XII secreted phospholipase A2|group XIIA secreted phospholipase A2
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