SNW1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human SNW1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human SNW1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human SNW1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — SNW1
Entrez GeneID
22938GeneBank Accession#
SNW1Gene Name
SNW1
Gene Alias
Bx42, MGC119379, NCOA-62, PRPF45, Prp45, SKIIP, SKIP
Gene Description
SNW domain containing 1
Omim ID
603055Gene Ontology
HyperlinkGene Summary
This gene, a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also function as a splicing factor by interacting with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity. [provided by RefSeq
Other Designations
SKI interacting protein|SKI-interacting protein|homolog of Drosophila BX42|nuclear protein SkiP|nuclear receptor coactivator, 62-kD
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