PSMD7 monoclonal antibody (M01), clone 2G5
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant PSMD7.
Immunogen
PSMD7 (AAH12606, 1 a.a. ~ 324 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MPELAVQKVVVHPLVLLSVVDHFNRIGKVGNQKRVVGVLLGSWQKKVLDVSNSFAVPFDEDDKDDSVWFLDHDYLENMYGMFKKVNARERIVGWYHTGPKLHKNDIAINELMKRYCPNSVLVIIDVKPKDLGLPTEAYISVEEVHDDGTPTSKTFEHVTSEIGAEEAEEVGVEHLLRDIKDTTVGTLSQRITNQVHGLKGLNSKLLDIRSYLEKVATGKLPINHQIIYQLQDVFNLLPDVSLQEFVKAFYLKTNDQMVVVYLASLIRSVVALHNLINNKIADRDAEKKEGQEKEESKKDRKEDKEKDKDKEKSDVKKEEKKEKK
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (97); Rat (96)
Isotype
IgG1 kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (61.38 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
PSMD7 monoclonal antibody (M01), clone 2G5. Western Blot analysis of PSMD7 expression in Hela S3 NE ( Cat # L013V3 ).Western Blot (Cell lysate)
PSMD7 monoclonal antibody (M01), clone 2G5 Western Blot analysis of PSMD7 expression in Jurkat ( Cat # L017V1 ).Western Blot (Recombinant protein)
ELISA
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Gene Info — PSMD7
Entrez GeneID
5713GeneBank Accession#
BC012606Protein Accession#
AAH12606Gene Name
PSMD7
Gene Alias
MOV34, P40, Rpn8, S12
Gene Description
proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
Omim ID
157970Gene Ontology
HyperlinkGene Summary
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 17. [provided by RefSeq
Other Designations
26S proteasome non-ATPase regulatory subunit 7|26S proteasome regulatory subunit S12|Moloney leukemia virus-34 proviral integration|Mov34 homolog|proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 (Mov34 homolog)|proteasome 26S non-ATPase subunit
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Interactome
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Pathway
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Disease
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