Products

Western Blot (Transfected lysate)

Immunofluorescence (Transfected cell)

Flow Cytometry (Transfected cell)

Entrez GeneID

GeneBank Accession#

Protein Accession#

Gene Name

ITPA

Gene Alias

C20orf37, HLC14-06-P, ITPase, dJ794I6.3

Gene Description

inosine triphosphatase (nucleoside triphosphate pyrophosphatase)

Omim ID

Gene Ontology

Gene Summary

The protein encoded by this gene hydrolyzes inosine triphosphate and deoxyinosine triphosphate to the monophosphate nucleotide and diphosphate. The encoded protein, which is a member of the HAM1 NTPase protein family, is found in the cytoplasm and acts as a homodimer. Defects in the encoded protein can result in inosine triphosphate pyrophosphorylase deficiency. Two transcript variants encoding two different isoforms have been found for this gene. Also, at least two other transcript variants have been identified which are probably regulatory rather than protein-coding. [provided by RefSeq

Other Designations

My049 protein|OTTHUMP00000030094|inosine triphosphatase|inosine triphosphatase-A|inosine triphosphate pyrophosphatase|inosine triphosphate pyrophosphohydrolase|nucleoside triphosphate diphosphatase|putative oncogene protein HLC14-06-P