CUTL1 monoclonal antibody (M01), clone 2A10
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant CUTL1.
Immunogen
CUTL1 (NP_001904.2, 521 a.a. ~ 620 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
AENRLAQHTLQALQSELDSLRADNIKLFEKIKFLQSYPGRGSGSDDTELRYSSQYEERLDPFSSFSKRERQRKYLSLSPWDKATLSMGRLVLSNKMARTI
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Rat (50)
Isotype
IgG1 kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.63 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of CUX1 expression in transfected 293T cell line by CUTL1 monoclonal antibody (M01), clone 2A10.
Lane 1: CUX1 transfected lysate(77.2 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of monoclonal antibody to CUTL1 on formalin-fixed paraffin-embedded human malignant lymphoma, diffuse large B tissue. [antibody concentration 5 ug/ml]Immunoprecipitation
Immunoprecipitation of CUX1 transfected lysate using anti-CUX1 monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with CUX1 MaxPab rabbit polyclonal antibody.Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged CUTL1 is approximately 0.03ng/ml as a capture antibody.ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to CUTL1 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — CUX1
Entrez GeneID
1523GeneBank Accession#
NM_001913Protein Accession#
NP_001904.2Gene Name
CUX1
Gene Alias
CASP, CDP, CDP/Cut, CDP1, COY1, CUTL1, CUX, Clox, Cux/CDP, GOLIM6, Nbla10317, p100, p110, p200, p75
Gene Description
cut-like homeobox 1
Omim ID
116896Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the homeodomain family of DNA binding proteins. It may regulate gene expression, morphogenesis, and differentiation and it may also play a role in the cell cycle progession. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq
Other Designations
cut homeobox|cut homolog|cut-like 1, CCAAT displacement protein|golgi integral membrane protein 6|putative protein product of Nbla10317
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Interactome
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Disease
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Publication Reference
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Prenatal low-dose methylmercury exposure causes premature neuronal differentiation and autism-like behaviors in a rodent model.
Allison Loan, Joseph Wai-Hin Leung, David P Cook, Chelsea Ko, Barbara C Vanderhyden, Jing Wang , Hing Man Chan.
iScience 2023 Jan; 26(3):106093.
Application:IHC, Mouse, Mouse brain cortex.
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The corepressor CtBP2 is required for proper development of the mouse cerebral cortex.
Esra Karaca, Xiaofei Li, Jakub Lewicki, Christina Neofytou, Nicolas Guérout, Fanie Barnabé-Heider, Ola Hermanson.
Molecular and Cellular Neurosciences 2020 Apr; 104:103481.
Application:IF, Mouse, Mouse cortex.
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Developmental and adult expression patterns of the G protein-coupled receptor GPR88 in the rat: Establishment of a dual nuclear-cytoplasmic localization.
Massart R, Mignon V, Stanic J, Munoz-Tello P, Becker JA, Kieffer BL, Darmon M, Sokoloff P, Diaz J.
The Journal of Comparative Neurology 2016 Oct; 524(14):2776.
Application:IF, Human, Mouse, Rat, Brain.
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Neocortical Layer Formation of Human Developing Brains and Lissencephalies: Consideration of Layer-Specific Marker Expression.
Saito T, Hanai S, Takashima S, Nakagawa E, Okazaki S, Inoue T, Miyata R, Hoshino K, Akashi T, Sasaki M, Goto YI, Hayashi M, Itoh M.
Cerebral Cortex (New York, N.Y. : 1991) 2011 Mar; 21(3):588.
Application:IHC-P, Human, Human brains.
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Prenatal low-dose methylmercury exposure causes premature neuronal differentiation and autism-like behaviors in a rodent model.
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