AKR1B1 293T Cell Transient Overexpression Lysate(Denatured)
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Specifications
Transfected Cell Line
293T
Plasmid
pCMV-AKR1B1 full-length
Host
Human
Theoretical MW (kDa)
34.87
Interspecies Antigen Sequence
Mouse (86); Rat (86)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-AKR1B1 antibody (H00000231-B01) by Western Blots.
Western Blot
Lane 1: AKR1B1 transfected lysate ( 34.76 KDa)
Lane 2: Non-transfected lysate.SDS-PAGE Gel
AKR1B1 transfected lysate.
Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — AKR1B1
Entrez GeneID
231GeneBank Accession#
BC000260Protein Accession#
AAH00260Gene Name
AKR1B1
Gene Alias
ADR, ALDR1, ALR2, AR, MGC1804
Gene Description
aldo-keto reductase family 1, member B1 (aldose reductase)
Omim ID
103880Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database. [provided by RefSeq
Other Designations
Lii5-2 CTCL tumor antigen|aldehyde reductase 1|aldo-keto reductase family 1, member B1|aldose reductase|low Km aldose reductase
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Interactomes
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