ACVR2B monoclonal antibody (MA03J), clone 1C11 (APC)

Catalog # H00000093-MA03J

Size

Price

Stock

Quantity

Size:3 x 50 ug
Price: USD $ 1,400.00
Stock:
order now, ship in 5 days
abnova-minus
abnova-plus
Size:50 ug
Price: USD $ 580.00
Stock:
order now, ship in 5 days
abnova-minus
abnova-plus

* The price is valid only in USA. Please select country.

Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
  • Specifications

    Product Description

    APC conjugated mouse monoclonal antibody raised against a partial recombinant ACVR2B.
    This product is belong to Cell Culture Grade Antibody (CX Grade).

    Immunogen

    ACVR2B (NP_001097, 21 a.a. ~ 120 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

    Sequence

    RGEAETRECIYYNANWELERTNQSGLERCEGEQDKRLHCYASWRNSSGTIELVKKGCWLDDFNCYDRQECVATEENPQVYFCCCEGNFCNERFTHLPEAG

    Host

    Mouse

    Reactivity

    Human

    Interspecies Antigen Sequence

    Mouse (99); Rat (99)

    Conjugation

    APC

    Preparation Method

    Cell Culture Production

    Isotype

    IgG2a Kappa

    Quality Control Testing

    Antibody Reactive Against Recombinant Protein.

    Storage Buffer

    In 1x PBS, pH 7.4

    Storage Instruction

    Store at 4°C.

  • Applications

    Flow Cytometry

    Western Blot

    Immunofluorescence

  • Gene Info — ACVR2B

    Entrez GeneID

    93

    GeneBank Accession#

    NM_001106

    Protein Accession#

    NP_001097

    Gene Name

    ACVR2B

    Gene Alias

    ACTRIIB, ActR-IIB, MGC116908

    Gene Description

    activin A receptor, type IIB

    Omim ID

    602730

    Gene Ontology

    Hyperlink

    Gene Summary

    Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. This gene encodes activin A type IIB receptor, which displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor. [provided by RefSeq

    Other Designations

    activin A type IIB receptor

  • Interactomes
  • Pathways
  • Diseases
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
4 Products to Compare
Remove All