ACPP purified MaxPab mouse polyclonal antibody (B01P)
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Specifications
Product Description
Mouse polyclonal antibody raised against a full-length human ACPP protein.
Immunogen
ACPP (NP_001090.2, 1 a.a. ~ 386 a.a) full-length human protein.
Sequence
MRAAPLLLARAASLSLGFLFLLFFWLDRSVLAKELKFVTLVFRHGDRSPIDTFPTDPIKESSWPQGFGQLTQLGMEQHYELGEYIRKRYRKFLNESYKHEQVYIRSTDVDRTLMSAMTNLAALFPPEGVSIWNPILLWQPIPVHTVPLSEDQLLYLPFRNCPRFQELESETLKSEEFQKRLHPYKDFIATLGKLSGLHGQDLFGIWSKVYDPLYCESVHNFTLPSWATEDTMTKLRELSELSLLSLYGIHKQKEKSRLQGGVLVNEILNHMKRATQIPSYKKLIMYSAHDTTVSGLQMALDVYNGLLPPYASCHLTELYFEKGEYFVEMYYRNETQHEPYPLMLPGCSPSCPLERFAELVGPVIPQDWSTECMTTNSHQGTEDSTD
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (82); Rat (81)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of ACPP expression in transfected 293T cell line (H00000055-T01) by ACPP MaxPab polyclonal antibody.
Lane 1: ACPP transfected lysate(42.46 KDa).
Lane 2: Non-transfected lysate.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of purified MaxPab antibody to ACPP on formalin-fixed paraffin-embedded human prostate. [antibody concentration 3 ug/ml] -
Gene Info — ACPP
Entrez GeneID
55GeneBank Accession#
NM_001099Protein Accession#
NP_001090.2Gene Name
ACPP
Gene Alias
ACP-3, ACP3, PAP
Gene Description
acid phosphatase, prostate
Omim ID
171790Gene Ontology
HyperlinkGene Summary
This gene encodes an enzyme that catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is synthesized under androgen regulation and is secreted by the epithelial cells of the prostate gland. An alternatively spliced transcript variant encoding a longer isoform has been found for this gene. This isoform contains a transmembrane domain and is localized in the plasma membrane-endosomal-lysosomal pathway. [provided by RefSeq
Other Designations
prostatic acid phosphotase
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Interactomes
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Pathways
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Diseases
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Publication Reference
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An evolutionarily conserved mode of modulation of Shaw-like K+ channels.
Cotella D, Hernandez-Enriquez B, Duan Z, Wu X, Gazula VR, Brown MR, Kaczmarek LK, Sesti F.
FASEB Journal 2013 Apr; 27(4):1381.
Application:IP-WB, Mouse, Brain.
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An evolutionarily conserved mode of modulation of Shaw-like K+ channels.
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