ACACB monoclonal antibody (M01A), clone 1C11
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More Files
- More Functions
Western Blot detection against Immunogen (36.63 KDa) .
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Specifications
Product Description
Mouse monoclonal antibody raised against a partial recombinant ACACB.
Immunogen
ACACB (NP_001084, 22 a.a. ~ 120 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
IWGKMTDSKPITKSKSEANLIPSQEPFPASDNSGETPQRNGEGHTLPKTPSQAEPASHKGPKDAGRRRNSLPPSHQKPPRNPLSSSDAAPSPELQANGT
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (57)
Isotype
IgM Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.63 KDa) .
Storage Buffer
In ascites fluid
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — ACACB
Entrez GeneID
32GeneBank Accession#
NM_001093Protein Accession#
NP_001084Gene Name
ACACB
Gene Alias
ACC2, ACCB, HACC275
Gene Description
acetyl-Coenzyme A carboxylase beta
Omim ID
601557Gene Ontology
HyperlinkGene Summary
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. ACC-beta is thought to control fatty acid oxidation by means of the ability of malonyl-CoA to inhibit carnitine-palmitoyl-CoA transferase I, the rate-limiting step in fatty acid uptake and oxidation by mitochondria. ACC-beta may be involved in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. There is evidence for the presence of two ACC-beta isoforms. [provided by RefSeq
Other Designations
acetyl-CoA carboxylase 2
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Interactomes
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Pathways
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Diseases
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