NAT2 (Human) Recombinant Protein (P02)
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More Files
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Specifications
Product Description
Human NAT2 full-length ORF ( AAH15878.1, 1 a.a. - 290 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MDIEAYFERIGYKNSRNKLDLETLTDILEHQIRAVPFENLNMHCGQAMELGLEAIFDHIVRRNRGGWCLQVNQLLYWALTTIGFQTTMLGGYFYIPPVNKYSTGMVHLLLQVTIDGRNYIVDAGSGSSSQMWQPLELISGKDQPQVPCIFCLTEERGIWYLDQIRREQYITNKEFLNSHLLPKKKHQKIYLFTLEPQTIEDFESMNTYLQTSPTSSFITTSFCSLQTPEGVYCLVGFILTYRKFNYKDNTDLVEFKTLTEEEVEEVLKNIFKISLGRNLVPKPGDGSLTI
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
59.9
Interspecies Antigen Sequence
Mouse (72); Rat (74)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — NAT2
Entrez GeneID
10GeneBank Accession#
BC015878.1Protein Accession#
AAH15878.1Gene Name
NAT2
Gene Alias
AAC2, PNAT
Gene Description
N-acetyltransferase 2 (arylamine N-acetyltransferase)
Omim ID
243400Gene Ontology
HyperlinkGene Summary
This gene encodes an enzyme that functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are responsible for the N-acetylation polymorphism in which human populations segregate into rapid, intermediate, and slow acetylator phenotypes. Polymorphisms in this gene are also associated with higher incidences of cancer and drug toxicity. A second arylamine N-acetyltransferase gene (NAT1) is located near this gene (NAT2). [provided by RefSeq
Other Designations
N-acetyltransferase 2|arylamide acetylase 2|arylamine N-acetyltransferase 2
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Interactomes
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Pathways
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Diseases
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