NAT2 monoclonal antibody (M01), clone 3B5
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More Files
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Specifications
Product Description
Mouse monoclonal antibody raised against a partial recombinant NAT2.
Immunogen
NAT2 (AAH15878, 96 a.a. ~ 195 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
PPVNKYSTGMVHLLLQVTIDGRNYIVDAGSGSSSQMWQPLELISGKDQPQVPCIFCLTEERGIWYLDQIRREQYITNKEFLNSHLLPKKKHQKIYLFTLE
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (72); Rat (74)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.63 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of NAT2 expression in transfected 293T cell line by NAT2 monoclonal antibody (M01), clone 3B5.
Lane 1: NAT2 transfected lysate(33.5 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
ELISA
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Gene Info — NAT2
Entrez GeneID
10GeneBank Accession#
BC015878Protein Accession#
AAH15878Gene Name
NAT2
Gene Alias
AAC2, PNAT
Gene Description
N-acetyltransferase 2 (arylamine N-acetyltransferase)
Omim ID
243400Gene Ontology
HyperlinkGene Summary
This gene encodes an enzyme that functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are responsible for the N-acetylation polymorphism in which human populations segregate into rapid, intermediate, and slow acetylator phenotypes. Polymorphisms in this gene are also associated with higher incidences of cancer and drug toxicity. A second arylamine N-acetyltransferase gene (NAT1) is located near this gene (NAT2). [provided by RefSeq
Other Designations
N-acetyltransferase 2|arylamide acetylase 2|arylamine N-acetyltransferase 2
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Interactomes
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Pathways
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Diseases
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