NAT2 purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
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Specifications
Product Description
Rabbit polyclonal antibody raised against a full-length human NAT2 protein.
Immunogen
NAT2 (AAH15878.1, 1 a.a. ~ 290 a.a) full-length human protein.
Sequence
MDIEAYFERIGYKNSRNKLDLETLTDILEHQIRAVPFENLNMHCGQAMELGLEAIFDHIVRRNRGGWCLQVNQLLYWALTTIGFQTTMLGGYFYIPPVNKYSTGMVHLLLQVTIDGRNYIVDAGSGSSSQMWQPLELISGKDQPQVPCIFCLTEERGIWYLDQIRREQYITNKEFLNSHLLPKKKHQKIYLFTLEPQTIEDFESMNTYLQTSPTSSFITTSFCSLQTPEGVYCLVGFILTYRKFNYKDNTDLVEFKTLTEEEVEEVLKNIFKISLGRNLVPKPGDGSLTI
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (72); Rat (74)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of NAT2 expression in transfected 293T cell line (H00000010-T01) by NAT2 MaxPab polyclonal antibody.
Lane 1: NAT2 transfected lysate(33.50 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — NAT2
Entrez GeneID
10GeneBank Accession#
BC015878.1Protein Accession#
AAH15878.1Gene Name
NAT2
Gene Alias
AAC2, PNAT
Gene Description
N-acetyltransferase 2 (arylamine N-acetyltransferase)
Omim ID
243400Gene Ontology
HyperlinkGene Summary
This gene encodes an enzyme that functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are responsible for the N-acetylation polymorphism in which human populations segregate into rapid, intermediate, and slow acetylator phenotypes. Polymorphisms in this gene are also associated with higher incidences of cancer and drug toxicity. A second arylamine N-acetyltransferase gene (NAT1) is located near this gene (NAT2). [provided by RefSeq
Other Designations
N-acetyltransferase 2|arylamide acetylase 2|arylamine N-acetyltransferase 2
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Interactomes
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Pathways
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Diseases
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