FGF23/CEN12p FISH Probe

Catalog # FG0001

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Size:100 uL
Price: USD $ 1,288.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
Images
Fluorescent <i>In Situ</i> Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
Application

Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)

Human uterus cancer (FFPE) stained with FGF23/CEN12p FISH Probe. Human uterus cancer showed FGF23 gene amplification.

QC Test

<br>Hybridization position of the probes on the chromosome.
Note


Hybridization position of the probes on the chromosome.


Hybridization position of the probes on the chromosome.

  • Specification

    Product Description

    Labeled FISH probes for identification of gene amplification using Fluoresecent In Situ Hybridization Technique. (Technology)

    Probe 1

    Name: FGF23
    Size: Approximately 300kb
    Fluorophore: Texas Red
    Location: 12p13

    Probe 2

    Name: CEN12p
    Size: Approximately 530kb
    Fluorophore: FITC
    Location: 12p11.22

    Probe Gap

    The gap between two probes is approximately 25,100 kb.

    Origin

    Human

    Source

    Genomic DNA

    Reactivity

    Human

    Form

    Liquid

    Notice

    We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.

    Regulation Status

    For research use only (RUO)

    Quality Control Testing

    Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.

    Supplied Product

    DAPI Counterstain (1500 ng/mL ) 125 uL for each 100 uL FISH Probe

    Storage Instruction

    Store at 4°C in the dark.

    Note


    Hybridization position of the probes on the chromosome.

  • Applications

    Fluorescent In Situ Hybridization (Cell)

    Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)

    Human uterus cancer (FFPE) stained with FGF23/CEN12p FISH Probe. Human uterus cancer showed FGF23 gene amplification.
  • Gene Info — FGF23

    Entrez GeneID

    8074

    Gene Name

    FGF23

    Gene Alias

    ADHR, HPDR2, HYPF, PHPTC

    Gene Description

    fibroblast growth factor 23

    Omim ID

    193100 211900 605380

    Gene Ontology

    Hyperlink

    Gene Summary

    The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The product of this gene inhibits renal tubular phosphate transport. This gene was identified by its mutations associated with autosomal dominant hypophosphatemic rickets (ADHR), an inherited phosphate wasting disorder. Abnormally high level expression of this gene was found in oncogenic hypophosphatemic osteomalacia (OHO), a phenotypically similar disease caused by abnormal phosphate metabolism. Mutations in this gene have also been shown to cause familial tumoral calcinosis with hyperphosphatemia. [provided by RefSeq

    Other Designations

    tumor-derived hypophosphatemia inducing factor

  • Interactome
  • Pathway
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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