ATP7B recombinant monoclonal antibody, clone 24A4
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More Files
- More Functions
Immunofluorescence
Immunofluorescence staining of Hela Cells with ATP7B recombinant monoclonal antibody, clone 24A4 at 1:100, counter-stained with DAPI.
Flow Cytometry
Overlay Peak curve showing Hela cells stained with ATP7B recombinant monoclonal antibody, clone 24A4 (red line) at 1:100.
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human ATP7B.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human ATP7B.
Reactivity
Human
Form
Liquid
Purification
Affinity chromatography purification
Isotype
IgG
Recommend Usage
ELISA
Flow Cytometry(1:50-1:200)
Immunofluorescence(1:20-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH7.4 (150 mM NaCl, 0.02% sodium azide and 50% glycerol)
Storage Instruction
Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunofluorescence
Immunofluorescence staining of Hela Cells with ATP7B recombinant monoclonal antibody, clone 24A4 at 1:100, counter-stained with DAPI.Enzyme-linked Immunoabsorbent Assay
Flow Cytometry
Overlay Peak curve showing Hela cells stained with ATP7B recombinant monoclonal antibody, clone 24A4 (red line) at 1:100. -
Gene Info — ATP7B
Entrez GeneID
540Protein Accession#
P35670Gene Name
ATP7B
Gene Alias
PWD, WC1, WD, WND
Gene Description
ATPase, Cu++ transporting, beta polypeptide
Gene Ontology
HyperlinkGene Summary
This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD). [provided by RefSeq
Other Designations
ATPase, Cu(2+)- transporting, beta polypeptide|OTTHUMP00000040880|Wilson disease-associated protein|copper pump 2|copper-transporting ATPase 2
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Interactome
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Disease
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