NAIP recombinant monoclonal antibody, clone 13E6
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human NAIP.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human NAIP.
Reactivity
Human
Form
Liquid
Purification
Affinity chromatography purification
Isotype
IgG
Recommend Usage
ELISA
Immunohistochemistry(1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH7.4 (150 mM NaCl, 0.02% sodium azide and 50% glycerol)
Storage Instruction
Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry
Immunohistochemistry image of NAIP recombinant monoclonal antibody, clone 13E6 diluted at 1:80 and staining in paraffin-embedded human placenta tissue performed on a Leica BondTM system.Enzyme-linked Immunoabsorbent Assay
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Gene Info — NAIP
Entrez GeneID
4671Protein Accession#
Q13075Gene Name
NAIP
Gene Alias
BIRC1, FLJ18088, FLJ42520, FLJ58811, NLRB1, psiNAIP
Gene Description
NLR family, apoptosis inhibitory protein
Omim ID
600355Gene Ontology
HyperlinkGene Summary
This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This copy of the gene is full length; additional copies with truncations and internal deletions are also present in this region of chromosome 5q13. It is thought that this gene is a modifier of spinal muscular atrophy caused by mutations in a neighboring gene, SMN1. The protein encoded by this gene contains regions of homology to two baculovirus inhibitor of apoptosis proteins, and it is able to suppress apoptosis induced by various signals. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq
Other Designations
NLR family, BIR domain containing 1|OTTHUMP00000125255|baculoviral IAP repeat-containing 1|neuronal apoptosis inhibitory protein|nucleotide-binding oligomerization domain, leucine rich repeat and BIR domain containing 1|psi neuronal apoptosis inhibitory p
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Interactome
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Disease
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