XPO1 recombinant monoclonal antibody, clone 9F2

Catalog # RAB07403

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Size:100 uL
Price: USD $ 638.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Application

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

Immunohistochemical analysis of paraffin-embedded human brain tissue using XPO1 recombinant monoclonal antibody, clone 9F2 (Cat # RAB07403) on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

  • Specification

    Product Description

    Rabbit recombinant monoclonal antibody raised against human XPO1.Recombinant Antibody,Recombinant Antibodies,Recombinant Monoclonal Antibody,RecomAb,Recombinant Ab,Recombinant Monoclonal Antibodies,Recombinant Abs

    Antibody Species

    Rabbit

    Immunogen

    Original antibody is raised against a synthetic peptide corresponding to human XPO1.

    Reactivity

    Human

    Form

    Liquid

    Purification

    Affinity chromatography purification

    Isotype

    IgG

    Recommend Usage

    ELISA
    Immunohistochemistry (1:50-1:200)
    The optimal working dilution should be determined by the end user.

    Storage Buffer

    In PBS, pH7.4 (150 mM NaCl, 0.02% sodium azide and 50% glycerol)

    Storage Instruction

    Store at -20°C or -80°C.
    Aliquot to avoid repeated freezing and thawing.

    Note

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

  • Applications

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

    Immunohistochemical analysis of paraffin-embedded human brain tissue using XPO1 recombinant monoclonal antibody, clone 9F2 (Cat # RAB07403) on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

    Enzyme-linked Immunoabsorbent Assay

  • Gene Info — XPO1

    Entrez GeneID

    7514

    Protein Accession#

    O14980

    Gene Name

    XPO1

    Gene Alias

    CRM1, DKFZp686B1823

    Gene Description

    exportin 1 (CRM1 homolog, yeast)

    Omim ID

    602559

    Gene Ontology

    Hyperlink

    Gene Summary

    The protein encoded by this gene mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1. [provided by RefSeq

    Other Designations

    CRM1, yeast, homolog|Exportin-1 (required for chromosome region maintenance)|exportin 1|exportin 1 (CRM1, yeast, homolog)

  • Interactome
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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