TFR2 recombinant monoclonal antibody, clone R04-7T7
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human Transferrin Receptor 2.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to human Transferrin Receptor 2
Theoretical MW (kDa)
Calculated MW: 89 kD
Reactivity
Human
Form
Liquid
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)(1/50-1/100)
Western Blot (1/500-1/1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150mM NaCl, pH 7.4 (50% glycerol and 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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Gene Info — TFR2
Entrez GeneID
7036Gene Name
TFR2
Gene Alias
HFE3, MGC126368, TFRC2
Gene Description
transferrin receptor 2
Gene Ontology
HyperlinkGene Summary
This gene is a member of the transferrin receptor-like family and encodes a single-pass type II membrane protein with a protease associated (PA) domain, an M28 peptidase domain and a transferrin receptor-like dimerization domain. This protein mediates cellular uptake of transferrin-bound iron and mutations in this gene have been associated with hereditary hemochromatosis type III. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq
Other Designations
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Interactome
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Disease
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