PRC1 recombinant monoclonal antibody, clone R04-3G7
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human PRC1.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human PRC1.
Theoretical MW (kDa)
72
Reactivity
Human, Rat
Form
Liquid
Purification
Affinity chromatography
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-1:100)
Immunoprecipitation(1:20)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot (Cell lysate)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoprecipitation
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Gene Info — PRC1
Entrez GeneID
9055Protein Accession#
O43663Gene Name
PRC1
Gene Alias
ASE1, MGC1671, MGC3669
Gene Description
protein regulator of cytokinesis 1
Omim ID
603484Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that is involved in cytokinesis. The encoded protein is at high level during S and G2/M and drop dramatically after cell exit mitosis and enter G1. It is located in the nucleus during interphase, and becomes associated with mitotic spindles in a highly dynamic manner during mitosis, and localizes to the cell mid-body during cytokinesis. This protein has been shown to be a substrate of several cyclin-dependent kinases (CDKs). At least three alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq
Other Designations
anaphase spindle elongation 1 homolog|protein regulating cytokinesis 1
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Interactome
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