GLUL recombinant monoclonal antibody, clone R03-4B6
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More Files
- More Functions
Western Blot
Western Blot analysis of mouse brain lysates with Glutamine Synthetase recombinant monoclonal antibody, clone R03-4B6 (Cat # RAB01698).
Western Blot
Western blot analysis of Glutamine Synthetase in rat Brain lysates using human Glutamine Synthetase recombinant monoclonal antibody, clone R03-4B6 (Cat # RAB01698).
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against synthetic peptide of human Glutamine Synthetase.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human Glutamine Synthetase
Theoretical MW (kDa)
Calculated MW: 42 kD
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Western Blot (1:500-1:1,000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM Tris-Glycine, pH 7.4 (0.15 M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western Blot analysis of mouse brain lysates with Glutamine Synthetase recombinant monoclonal antibody, clone R03-4B6 (Cat # RAB01698).Western Blot
Western blot analysis of Glutamine Synthetase in rat Brain lysates using human Glutamine Synthetase recombinant monoclonal antibody, clone R03-4B6 (Cat # RAB01698). -
Gene Info — GLUL
Entrez GeneID
2752Protein Accession#
P15104Gene Name
GLUL
Gene Alias
GLNS, GS, PIG43, PIG59
Gene Description
glutamate-ammonia ligase (glutamine synthetase)
Gene Ontology
HyperlinkGene Summary
Glutamine is a main source of energy and is involved in cell proliferation, inhibition of apoptosis, and cell signaling (Haberle et al., 2005 [PubMed 16267323]). Fetal glutamine requirements are very high and depend largely on active glutamine synthesis and the release of glutamine into the fetal circulation by the placenta. Glutamine synthetase (EC 6.3.1.2), also called glutamate-ammonia ligase (GLUL), is expressed throughout the body and plays an important role in controlling body pH and in removing ammonia from the circulation. The enzyme clears L-glutamate, the major neurotransmitter in the central nervous system, from neuronal synapses (see references in Clancy et al., 1996 [PubMed 8975719]).[supplied by OMIM
Other Designations
OTTHUMP00000035524|OTTHUMP00000035525|cell proliferation-inducing protein 59|glutamate-ammonia ligase (glutamine synthase)|glutamine synthetase|proliferation-inducing protein 43
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Interactome
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Pathway
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Disease
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