CLDN7 polyclonal antibody
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Specifications
Product Description
Rabbit polyclonal antibody raised against partial recombinant human CLDN7.
Immunogen
Recombinant protein corresponding to human CLDN7.
Sequence
PQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTGMMSCKMYDSVLALS
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:20-1:50)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human rectum with CLDN7 polyclonal antibody (Cat # PAB30489) shows strong membranous and cytoplasmic positivity in glandular cells at 1:20-1:50 dilution. -
Gene Info — CLDN7
Entrez GeneID
1366Protein Accession#
O95471Gene Name
CLDN7
Gene Alias
CEPTRL2, CPETRL2, Hs.84359, claudin-1
Gene Description
claudin 7
Omim ID
609131Gene Ontology
HyperlinkGene Summary
Claudins, such as CLDN7, are involved in the formation of tight junctions between epithelial cells. Tight junctions restrict lateral diffusion of lipids and membrane proteins, and thereby physically define the border between the apical and basolateral compartments of epithelial cells (Zheng et al., 2003 [PubMed 14502431]).[supplied by OMIM
Other Designations
Clostridium perfringens enterotoxin receptor-like 2|claudin 9
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