LMNB1 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
LMNB1 polycolnal antibody (Cat # PAB27538) (1ug/ml) staining of nuclear HeLa lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of LMNB1.
Immunogen
A synthetic peptide corresponding to amino acids 526-537 near C-terminus region of human LMNB1.
Sequence
DVKVILKNSQGE
Host
Goat
Theoretical MW (kDa)
70
Reactivity
Chicken, Dog, Human, Mouse, Pig
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:64000)
Western Blot (0.3-1ug/ml)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
LMNB1 polycolnal antibody (Cat # PAB27538) (1ug/ml) staining of nuclear HeLa lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. -
Gene Info — LMNB1
Entrez GeneID
4001Protein Accession#
NP_005564.1;NP_001185486.1Gene Name
LMNB1
Gene Alias
ADLD, LMN, LMN2, LMNB, MGC111419
Gene Description
lamin B1
Gene Ontology
HyperlinkGene Summary
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. [provided by RefSeq
Other Designations
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Interactome
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Disease
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