AMHR2 (Human) Recombinant Protein
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More Files
- More Functions
Enzyme-linked Immunoabsorbent Assay
Immobilized Human AMHRII, hFc Tag at 0.5 ug/mL (100 uL/well) on the plate. Dose response curve for Biotinylated Anti-AMHRII Antibody, hFc Tag with the EC50 of 86.4 ng/mL determined by ELISA.
SEC-HPLC
The purity of Human AMHRII is greater than 95% as determined by SEC-HPLC.
Tris-Bis PAGE
Human AMHRII on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
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Specification
Product Description
Human AMHR2 (Q16671-1, Pro18-Ser144) partial recombinant protein with hFc tag at C-Terminus expressed in HEK293 cells.
Sequence
Pro18-Ser144
Host
Human
Theoretical MW (kDa)
40.2
Form
Lyophilized
Preparation Method
Mammalian cell (HEK293) expression system
Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin Level
< 1 EU per 1 ug of protein (determined by LAL method)
Activity
The EC50 was 86.4 ng/mL, messured by ELISA at 0.5 ug/mL.
Quality Control Testing
SEC-HPLC and Tris-Bis PAGE
SEC-HPLC
The purity of Human AMHRII is greater than 95% as determined by SEC-HPLC.
Tris-Bis PAGE
Human AMHRII on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
Recommend Usage
Biological Activity
ELISA
SDS-PAGE
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from sterile distilled Water is > 100 ug/mL
Storage Instruction
Store at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing.Note
Result of bioactivity analysis
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Applications
Enzyme-linked Immunoabsorbent Assay
Immobilized Human AMHRII, hFc Tag at 0.5 ug/mL (100 uL/well) on the plate. Dose response curve for Biotinylated Anti-AMHRII Antibody, hFc Tag with the EC50 of 86.4 ng/mL determined by ELISA.Functional Study
SDS-PAGE
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Gene Info — AMHR2
Entrez GeneID
269Protein Accession#
Q16671-1Gene Name
AMHR2
Gene Alias
AMHR, MISR2, MISRII
Gene Description
anti-Mullerian hormone receptor, type II
Gene Ontology
HyperlinkGene Summary
This gene encodes the receptor for the anti-Mullerian hormone (AMH) which, in addition to testosterone, results in male sex differentiation. AMH and testosterone are produced in the testes by different cells and have different effects. Testosterone promotes the development of male genitalia while the binding of AMH to the encoded receptor prevents the development of the mullerian ducts into uterus and Fallopian tubes. Mutations in this gene are associated with persistent Mullerian duct syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
Other Designations
Mullerian inhibiting substance type II receptor
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Interactome
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Pathway
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Disease
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