RIPK3 monoclonal antibody, clone Rippy-3
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More Files
- More Functions
Western Blot (Transfected lysate)
Detection of human RIPK3. HEK 293T cells (5 X 105) mock transfected (lane 1) or transfected (lane 2) with an expression plasmid coding for human RIPK3. Incubated with the RIPK3 monoclonal antibody, clone Rippy-3 (Cat # MAB3728) at a 1 : 1,000 dilution.
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant RIPK3.
Immunogen
Recombinant protein corresponding to human RIPK3.
Host
Mouse
Reactivity
Human
Specificity
Recognizes human RIP3.
Form
Liquid
Isotype
IgG1
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Detection of human RIPK3. HEK 293T cells (5 X 105) mock transfected (lane 1) or transfected (lane 2) with an expression plasmid coding for human RIPK3. Incubated with the RIPK3 monoclonal antibody, clone Rippy-3 (Cat # MAB3728) at a 1 : 1,000 dilution. -
Gene Info — RIPK3
Entrez GeneID
11035Gene Name
RIPK3
Gene Alias
RIP3
Gene Description
receptor-interacting serine-threonine kinase 3
Omim ID
605817Gene Ontology
HyperlinkGene Summary
The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor. [provided by RefSeq
Other Designations
RIP-like protein kinase 3|receptor interacting protein 3
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Interactome
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Disease
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