HNRNPA2B1 monoclonal antibody, clone DP3B3
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot for HNRNPA2B1 monoclonal antibody, clone DP3B3 (Cat # MAB2497) on HeLa cell extract.
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant HNRNPA2B1.
Immunogen
Recombinant His fusion protein corresponding to human HNRNPA2B1.
Host
Mouse
Theoretical MW (kDa)
36, 38
Reactivity
Chicken, Human, Mouse
Specificity
Cross reacts with mouse for IHC on lung tissue. Reacts predominantly with a 36 KDa band (A2), & a 38 KDa band (B1).
Form
Liquid
Isotype
IgG2a
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Recommend Usage
Western Blot (1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot for HNRNPA2B1 monoclonal antibody, clone DP3B3 (Cat # MAB2497) on HeLa cell extract.Immunohistochemistry
Immunofluorescence
Immunoprecipitation
Enzyme-linked Immunoabsorbent Assay
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Gene Info — HNRNPA2B1
Entrez GeneID
3181Gene Name
HNRNPA2B1
Gene Alias
DKFZp779B0244, FLJ22720, HNRNPA2, HNRNPB1, HNRPA2, HNRPA2B1, HNRPB1, RNPA2, SNRPB1
Gene Description
heterogeneous nuclear ribonucleoprotein A2/B1
Omim ID
600124Gene Ontology
HyperlinkGene Summary
This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. This gene has been described to generate two alternatively spliced transcript variants which encode different isoforms. [provided by RefSeq
Other Designations
heterogeneous nuclear ribonucleoprotein B1|nuclear ribonucleoprotein particle A2 protein
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Interactome
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Publication Reference
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Diagnostic and prognostic values of PBMC proteins in amyotrophic lateral sclerosis.
Luotti S, Pasetto L, Porcu L, Torri V, Elezgarai SR, Pantalone S, Filareti M, Corbo M, Lunetta C, Mora G, Bonetto V.
Neurobiology of Disease 2020 Jun; 139:10481.
Application：WB-Ce, Human, PBMCs.
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Altered expression of splicing factor, heterogeneous nuclear ribonucleoprotein A2/B1, in mouse lung neoplasia.
Peebles KA, Dwyer-Nield LD, Malkinson AM.
Molecular Carcinogenesis 2007 Nov; 46(11):887.
Application：IHC, WB, Mouse, Mouse Clara cells, Lung tissues, Type 2 cells.
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Protein composition of the intranuclear inclusions of FXTAS.
Iwahashi CK, Yasui DH, An HJ, Greco CM, Tassone F, Nannen K, Babineau B, Lebrilla CB, Hagerman RJ, Hagerman PJ.
Brain 2006 Jan; 129(Pt 1):256.
Application：IF, Human, Inclusions from frontal cortex of patients with Fragile X-associated tremor/ataxia syndrome.
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beta-catenin interacts with the FUS proto-oncogene product and regulates pre-mRNA splicing.
Sato S, Idogawa M, Honda K, Fujii G, Kawashima H, Takekuma K, Hoshika A, Hirohashi S, Yamada T.
Gastroenterology 2005 Oct; 129(4):1225.
Application：WB, Human, DLD-1 cells.
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Diagnostic and prognostic values of PBMC proteins in amyotrophic lateral sclerosis.
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